NeoGenesis Skin Serum Regenerative Support  20% S²RM® - SKIN ACCORD
NeoGenesis Skin Serum Regenerative Support  20% S²RM® - SKIN ACCORD
NeoGenesis Recovery Serum Advanced Cellular Serum 70% S²RM® - SKIN ACCORD
NeoGenesis Skin Serum Regenerative Support  20% S²RM® - SKIN ACCORD
NeoGenesis Skin Serum Regenerative Support  20% S²RM® - SKIN ACCORD
NeoGenesis Recovery Serum Advanced Cellular Serum 70% S²RM® - SKIN ACCORD

NeoGenesis Skin Serum Regenerative Support 20% S²RM®

$82.50
Size 15 ml
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NeoGenesis Skin Serum is a daily serum that uses twenty percent S²RM®, a complex of signaling molecules released from adult human skin stem cells and fibroblasts. These molecules include proteins, peptides, growth factors, and enzymes that are naturally packaged inside tiny lipid bubbles called exosomes, which the skin uses for cell to cell communication and repair signals.

 

In this formula, the S²RM complex sits in a hydrating base of propanediol and glycerin that draw water into the outer layers of the skin, while gluconolactone provides gentle surface refining and Chinese Senna seed extract helps hold moisture at the surface like a plant based version of hyaluronic acid. With regular use, Skin Serum helps the skin look smoother and more even, softens the appearance of fine lines and texture, and brings back a calm, comfortable, well hydrated feel without heaviness. 

 

Skin Serum is a great place to start with NeoGenesis S²RM® technology, and many clients choose to step up to Booster after they experience what Skin Serum does for their skin.

 

How It Works

Skin Serum features S²RM® technology at a twenty percent concentration. S²RM® is a complex of molecules released by cultured adult human skin stem cells and fibroblasts, including signaling proteins, peptides, growth factors, lipids, enzymes, and antioxidant molecules that are naturally packaged inside tiny lipid vesicles called exosomes.

These stem cell released molecules sit in a hydrating base with propanediol, glycerin, and Chinese senna seed extract, which help attract and hold water at the surface of the skin. Together, they support more balanced communication in the outer layers of the skin while replenishing surface hydration, so the complexion looks smoother, more even, and better supported day to day.

 

Frequently Asked Questions

How is Skin Serum different from NeoGenesis Recovery? Recovery contains a higher concentration of S²RM® and is formulated as an intensive treatment serum, often used during specific recovery windows or periods of skin stress. Skin Serum at 20% S²RM® is designed for daily use as an ongoing regenerative and hydrating step. Many clients use both — applying Recovery as needed and Skin Serum every morning and evening as the foundation of their routine.

 

How is this different from NeoGenesis Booster? Booster contains a higher concentration of S²RM® than Skin Serum and is designed for clients who want to intensify their results or target more advanced concerns. Skin Serum is an excellent starting point for those new to the NeoGenesis lineup, and many clients naturally progress to Booster after experiencing what Skin Serum does for their skin.

 

Does this serum work for aging skin? Yes. The S²RM® complex in Skin Serum supports the skin's own signaling and repair processes, which tend to slow with age. With consistent daily use it helps soften the appearance of fine lines and texture, supports a more even complexion, and helps the skin feel more resilient and comfortable over time.

 

Can I use this if I have sensitive skin? Yes. Skin Serum is formulated without harsh actives, synthetic fragrance, or aggressive exfoliants. The S²RM® complex works with the skin's own biology rather than disrupting it, making it a well-tolerated daily serum for most skin types including sensitive skin. As with any new product, patch test before full facial use.

 

What does the exosome delivery system mean for how this works? S²RM® molecules are naturally packaged inside exosomes, which are the same tiny lipid vesicles the skin already uses to carry signals between cells. When applied topically, these exosomes interact with the outer layers of the skin to support changes in local signaling around inflammation, barrier behavior, and surface repair. This is how a topically applied serum can deliver meaningful, visible results without injections or medical procedures.

 

Can I use Skin Serum while pregnant or breastfeeding? NeoGenesis Skin Serum does not contain retinoids, strong acids, or pharmaceutical actives. However, as with any skincare product used during pregnancy or while breastfeeding, we recommend consulting your healthcare provider before use.

 

Key Ingredients

S²RM Stem Cell Released Molecules
(Human Adipose Mesenchymal Stem Cell Conditioned Media, Human Fibroblast Conditioned Media)

A complex of molecules released from adult human skin stem cells and fibroblasts, including growth factors, cytokines, peptides, lipids, and antioxidant enzymes. Naturally carried in exosomes, these signals support the look of healthier, more refined, and more resilient skin.

Glycerin and Propanediol
Water binding humectants that draw moisture into the outer layers of the skin and improve the glide of the serum. They help keep the surface feeling soft, cushioned, and comfortably hydrated without weight.

Chinese Senna (Cassia Obtusifolia) Seed Extract
A polysaccharide rich botanical extract often compared to hyaluronic acid for its ability to hold water at the surface. It forms a light, flexible veil that helps maintain a smooth, supple feel after application.

Gluconolactone
A gentle polyhydroxy acid and chelating agent that supports formula stability while offering mild refining benefits, helping to improve the appearance of texture and clarity without a harsh sensation.

Directions

Apply to clean, dry skin. Use one to two pumps or a few drops and smooth over the face, neck, and décolletage. Allow the serum to absorb, then follow with your chosen moisturizer and sunscreen in the morning or with your night cream in the evening.

Skin Serum may be used morning and night. For a layered S²RM routine, apply Recovery first as a treatment serum when needed, follow with Skin Serum for daily regenerative support and hydration, then lock everything in with moisturizer.

Usage Caution

• For external use only.
• Avoid contact with eyes. If the product comes into contact with the eyes, rinse immediately with plenty of water.
• Stop use if irritation, redness, or swelling occurs and consult a medical professional if symptoms persist.
• Do not apply to broken or inflamed skin.
• Keep out of reach of children.
• Store in a cool, dry place away from direct sunlight and extreme temperatures.

Disclaimer: Individual results may vary. Products sold at Skin Accord are formulated by their respective manufacturers to support healthy, balanced skin, but sensitivity can occur when introducing new active ingredients.

If layering skincare from multiple brands, introduce one new product at a time and monitor how your skin responds. Using several potent actives such as exfoliants, retinoids, or acids within the same routine may increase the likelihood of irritation.

Patch Test

Before first use, apply a small amount of Recovery to a discreet area such as the inner arm or behind the ear and leave on for twenty four hours. If no redness, burning, or discomfort occurs, proceed with use as directed on the face or targeted area. If any irritation develops during the patch test, rinse the area with water and discontinue use.

FAQ

How does applying it topically still help?

 Because the active “secretome” is naturally packaged in exosomes that can interact with the outer and upper layers of the skin, changing local signaling (inflammation, barrier behavior, repair messages). Those changes propagate deeper, so you can get real-world improvements in redness, texture, and barrier without injections.

Is the formula encapsulated so that it penetrates?

 The actives are naturally encapsulated in exosomes, which are like built-in nano-liposomes from the stem cells themselves. NeoGenesis explicitly frames this exosome packaging as how they enhance protection and penetration. There isn’t a separate synthetic encapsulation system beyond that.

 

Shipping

Shipping 
We currently ship within the United States. Most orders are processed within 2 business days, but during weekends or high-volume periods, processing may take up to 4 business days. Once your order ships, you’ll receive a confirmation email with tracking details. Enjoy free US shipping on orders over $100. 

Disclaimer & Patch Test

Disclaimer: Individual results may vary. Products sold at Skin Accord are formulated by their respective manufacturers to support healthy, balanced skin, but sensitivity can occur when introducing new active ingredients.

If layering skincare from multiple brands, introduce one new product at a time and monitor how your skin responds. Using several potent actives—such as exfoliants, retinoids, or acids—within the same routine may increase the likelihood of irritation.

Patch Test: For first-time use, apply a small amount to a discreet area (such as the inner arm or behind the ear) and wait 24 hours before full application. If irritation, redness, or discomfort occurs, discontinue use.

Use as directed and discontinue if redness, stinging, or discomfort occurs. Skin Accord cannot assume responsibility for reactions that result from misuse, overuse, or combining incompatible products. Please consult a qualified medical professional if you experience persistent irritation.

By purchasing and using products sold at Skin Accord, you acknowledge that individual skin responses vary and agree to follow usage instructions carefully.